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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK9
All Species:
16.06
Human Site:
Y357
Identified Species:
32.12
UniProt:
P45984
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P45984
NP_001128516.1
424
48139
Y357
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
E
Chimpanzee
Pan troglodytes
Q95NE7
360
41475
D294
K
M
L
V
L
D
S
D
K
R
I
T
A
A
Q
Rhesus Macaque
Macaca mulatta
XP_001094539
426
47882
E359
W
K
E
L
I
Y
K
E
V
M
N
S
E
E
K
Dog
Lupus familis
XP_856169
424
48117
Y357
E
E
W
K
E
L
I
Y
K
E
V
L
D
W
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTU6
423
48171
I356
I
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
Rat
Rattus norvegicus
P49186
423
47998
I356
I
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505616
424
48223
Y357
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
E
Chicken
Gallus gallus
P79996
382
43990
L316
R
I
S
V
D
E
A
L
R
H
P
Y
I
T
V
Frog
Xenopus laevis
Q8QHK8
426
47910
Y357
E
E
W
K
E
L
I
Y
K
E
V
L
D
W
E
Zebra Danio
Brachydanio rerio
Q9DGD9
384
44121
H318
S
V
D
E
A
L
Q
H
P
Y
I
N
V
W
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92208
372
43008
E306
K
M
L
V
I
D
P
E
Q
R
I
S
V
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8WQG9
463
52867
S392
A
Q
A
R
D
L
L
S
R
M
L
V
I
D
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
84.7
99.2
N.A.
96.6
98.8
N.A.
97.8
88.9
79.8
71.6
N.A.
65
N.A.
55.7
N.A.
Protein Similarity:
100
57.7
91.5
100
N.A.
97.4
98.8
N.A.
99
90
87.7
81.8
N.A.
76.1
N.A.
66.5
N.A.
P-Site Identity:
100
6.6
0
93.3
N.A.
6.6
6.6
N.A.
100
0
93.3
13.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
20
100
N.A.
33.3
33.3
N.A.
100
13.3
100
33.3
N.A.
26.6
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
0
9
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
17
17
0
9
0
0
0
0
34
34
0
% D
% Glu:
34
50
25
9
34
25
0
17
0
34
17
0
9
9
42
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% H
% Ile:
17
9
0
0
17
0
34
17
0
0
25
0
17
0
0
% I
% Lys:
17
9
0
34
17
0
9
0
42
17
0
0
0
0
9
% K
% Leu:
0
0
17
9
9
50
25
9
0
0
9
17
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
17
0
17
17
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
9
% P
% Gln:
0
9
0
0
0
0
9
0
9
0
0
0
0
0
9
% Q
% Arg:
9
0
0
9
0
0
0
0
17
17
0
0
0
0
0
% R
% Ser:
9
0
9
0
0
0
9
9
0
0
0
17
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% T
% Val:
0
9
0
25
0
0
0
0
9
0
34
25
17
0
9
% V
% Trp:
9
0
34
17
0
0
0
0
0
0
0
0
0
42
17
% W
% Tyr:
0
0
0
0
0
9
0
34
17
9
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _